Plasma proteomics reveals the confounding effect of heparin administration on the analysis of candidate cardiovascular biomarkers - Cohort2

Several plasma proteins have been suggested as markers for a variety of cardiovascular conditions but fail to qualify in independent patient cohorts. One reason may relate to interference of medication on plasma protein levels. In the present study we applied a proteomic approach to identify plasma proteins that changed in concentration with heparin administration and therefore potentially may confound their as biomarkers in situations where heparin is used.