Investigation of the location and secretion features of Candida albicans enolase with monoclonal antibodies

The glycolytic enzyme enolase plays important role in the pathogenesis of <em>Candida albicans </em>infection, and has been also considered as a promising molecular marker for the diagnosis of invasive candidiasis. This study aimed to investigate the location and secretion features of <em>Candida</em> <em>albicans</em> enolase (CaEno) with a couple of specific monoclonal antibodies (mAbs). <br>

糖酵解酶烯醇化酶在白色念珠菌（Candida albicans）感染的发病机制中发挥关键作用，同时亦被视为侵袭性念珠菌病诊断的极具潜力的分子标志物。本研究旨在利用一对特异性单克隆抗体（monoclonal antibodies, mAbs）探究白色念珠菌烯醇化酶（CaEno）的定位与分泌特征。