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RNA sequencing of splenic B cell populations prevalent in Py-infected mice

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134548
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Purpose: To peform genome wide transcriptomic analyses and compare the expression profile among Plasmablasts, activated B cells and resting B cells obtained form the spleens of Plasmodium yoelli infected mice on day 10 12 C57BL/6 mice obtained from Jackson laboratories were infected with 1 million Plasmodium yoelii paratized RBCs. ON day 10 post infection, spleens were harvested and three different B cell populations ( plasmablasts, activated B cells and resting B cells) were flow sorted, total RNA extracted and sequenced.
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2021-04-10
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