Supplementary data of light and dark genes and cancer studies.

The spreadsheet contains the following results/datasets according to the sheet name. Pharos Data: The distribution of genes within each development level obtained from Pharos. Cancer studies: List and description of individual cancer studies from which our analyses are based. Cancer Mutations in each TDL: The number of cancers with mutations in each target development level (TDL) class related to Fig 1b. Specific Gene Mutations: Frequency of dark and light gene mutations across all cancer types for each gene. Percent Dark Gene Mutations: Percentage of dark gene mutations in each cancer type for each gene. Percent Light Gene Mutations: Percentage of light gene mutations in each cancer type for each gene. Common Essential Genes: Publication, antibody, and monoclonal antibody counts for common essential genes (both dark and light genes). Non-Essential Genes: Publication, antibody, and monoclonal antibody counts for non-essential genes (both dark and light genes). (XLSX)