Neutrophil degranulation

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

本事件系通过计算推理自另一物种中已证实的类似事件推断而来。该推断基于PANTHER的同源性映射。简而言之，对于所有参与物理实体（在输入、输出和催化剂中）均存在映射的同源或旁系同源物（对于复合物而言，至少75%的组成部分必须具有映射）的反应，将其推断至其他物种。此外，对于这些事件也进行了高级别事件的推断，以便于更便捷的导航。有关Reactome中事件推断的更多细节及注意事项，请参阅<a href='/electronic_inference_compara.html' target = 'NEW'>此处</a>。有关PANTHER的详细信息，亦请参考<a href='http://www.pantherdb.org/about.jsp' target='NEW'>此处</a>。

搜集汇总

背景与挑战

背景概述

该数据集描述了中性粒细胞脱颗粒的生物学过程，包括颗粒的形成、分类及其在免疫反应中的作用。数据基于从其他物种的推断，并引用了多篇研究文献来详细说明这一过程。