Transcriptomic analysis by RNA-seq unveils distinct gene expression profile of U397 cells depleted of NSPs. Transcriptomic analysis by RNA-seq unveils distinct gene expression profile of U397 cells depleted of NSPs
收藏NIAID Data Ecosystem2026-03-11 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA597899
下载链接
链接失效反馈官方服务：
资源简介：
Characterization of transcriptomic changes associated with genetic ablation of three neutrophil serine proteases (CTSG, ELANE, PRTN3). U937 cells depleted of CTSG, ELANE, and PRTN3 simultaneously (ΔNSPs) were generated using the CRISPR-Cas9 system and sgRNAs. RNA-Seq analysis revealed transcriptomic changes between control cells and ΔNSPs, with 170 and 220 genes up- or down-regulated respectively. Overall design: RNA-Seq analysis of three control lines of U937 cells and three independent clones of ΔNSPs U937 cells
创建时间：
2019-12-27
