Kidney function parameters measured at baseline, 4 and 8 weeks after transplantation.

Plasma and urine was collected at baseline, 4 and 8 weeks after transplantation. Both plasma creatinine and urea rose during follow-up after transplantation while the creatinine clearance was reduced in all groups. Although not significant, glycol-split heparin treatment seemed to result in higher plasma creatinine and urea and lower creatinine clearance compared to vehicle treated animals. Also kidney hypertrophy, a measure for worsening kidney condition, was highest in glycol-split heparin treated animals.