Genomic Resistance Mechanisms to a single dose of PD-1 Blockade

NIAID Data Ecosystem2026-03-10 收录

肿瘤免疫治疗

全外显子测序分析

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA510621 数据链接链接失效反馈

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Paired DNA WES data from post treatment (D21) tumors and Recurrence tumors for three patients that recurred on the neoadjuvant pembrolizumab clinical trial NCT02434354.

创建时间：

2018-12-18

Table 3_Genetic analysis and clinical characteristics of sporadic and familial congenital cataracts in southern Chinese families.xlsx

白内障遗传学

全外显子测序分析

IntroductionCongenital cataract is a major cause of blindness and severe visual impairment in children. It may occur as an isolated ocular abnormality or in combination with microcornea, microphthalmi

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肿瘤免疫治疗

Wnt信号通路抑制剂

Aberrant activation of the Wnt/β-catenin signaling is associated with tumor development, and blocking β-catenin/BCL9 is a novel strategy for oncogenic Wnt/β-catenin signaling. Herein, we presented two

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Additional file 9: Table S10. of Metronomic cyclophosphamide activation of anti-tumor immunity: tumor model, mouse host, and drug schedule dependence of gene responses and their upstream regulators

肿瘤免疫治疗

药物基因组学

Differential gene responses to CPA in GL261(scid) and GL261(B6) tumors. (XLSX 2296 kb)

Figshare2017-03-10 更新00

In Vivo CRISPR Screening for metabolic regulators of immunotherapy. Mus musculus

肿瘤免疫治疗

代谢基因调控

To systematically study the functions of metabolic genes in regulating anti-tumor immunity, we performed a series of in vivo metabolic-wide CRISPR screens in orthotopic lung tumor mice models. We cons

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Fc-enhanced anti-CTLA-4 targets tumor-infiltrating regulatory T cells to augment immune effects of androgen ablation in high-risk prostate cancer

肿瘤免疫治疗

单细胞转录组学

Single-cell RNA-Sequencing Data and analysis code used for analyses performed in the manuscript "Fc-enhanced anti-CTLA-4 depletes tumor-infiltrating regulatory T cells to augment immune effects of and

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Genomic Resistance Mechanisms to a single dose of PD-1 Blockade

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