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cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol.

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Protein Data Bank Japan2025-06-25 更新2026-03-21 收录
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cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol. Descriptor: 25-HYDROXYCHOLESTEROL, Insulin-induced gene 2 protein, Sterol regulatory element-binding protein cleavage-activating protein,Sterol regulatory element-binding protein cleavage-activating protein Authors: Yan, R, Cao, P, Song, W, Qian, H, Du, X, Coates, H.W, Zhao, X, Li, Y, Gao, S, Gong, X, Liu, X, Sui, J, Lei, J, Yang, H, Brown, A.J, Zhou, Q, Yan, C, Yan, N. Deposit date: 2020-03-06 Release date: 2021-01-20 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science, 371, 2021
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2020-03-06
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