Structure of PDGFRb Kinase Domain Bound to JNJ-PDGFRBi-1

Structure of PDGFRb Kinase Domain Bound to JNJ-PDGFRBi-1 Descriptor: N-[2-(2,2-dimethylpyrrolidin-1-yl)ethyl]-6-methyl-5-({1-methyl-6-[(1-methyl-1H-pyrazol-4-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}amino)pyridine-3-carboxamide, Platelet-derived growth factor receptor beta Authors: Shaffer, P.L, Duda, D. Deposit date: 2026-03-13 Release date: 2026-05-20 Last modified: 2026-07-15 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Identification of an Inhaled Pulmonary Selective PDGFR Inhibitor with Sustained Target Engagement. J Aerosol Med Pulm Drug Deliv, 2026