Association between TCF7L2 variants and significant coronary artery disease in the total cohort.

Additive odds ratios (OR), 95% confidence intervals (CI), and p-values were calculated by logistic regression analyses: * Unadjusted. † Adjusted for age, gender, BMI, smoking, hypertension, serum levels of HDL cholesterol, LDL cholesterol, as well as for statin use. ‡ Adjusted for the same covariates as in model (†) and additionally for serum insulin, plasma glucose, haemoglobin A1c, and anti-diabetic medication. CAD indicates coronary artery disease. T2DM indicates type 2 diabetes mellitus.