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HIV-1 Integrase Catalytic Core Domain (CCD) F185H/Y99H/A128T Mutant Complexed with STP03-0404

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Protein Data Bank Japan2024-07-31 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8t5a
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HIV-1 Integrase Catalytic Core Domain (CCD) F185H/Y99H/A128T Mutant Complexed with STP03-0404 Descriptor: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase Authors: Dinh, T, Kvaratskhelia, M. Deposit date: 2023-06-12 Release date: 2024-06-19 Last modified: 2024-07-31 Method: X-RAY DIFFRACTION (1.93 Å) Cite: The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. Biorxiv, 2024
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2023-06-12
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