Cryo-EM structure of human Nav1.6 in complex with delta-paraponeritoxin-Pc1a

Cryo-EM structure of human Nav1.6 in complex with delta-paraponeritoxin-Pc1a Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yang, L, Fan, X, Huang, J, Yan, N. Deposit date: 2026-04-06 Release date: 2026-05-20 Last modified: 2026-08-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Diverse binding poses of agonistic neurotoxins on human Na v 1.6. Nature, 656, 2026