Summary of clinical AEs by cohorta.
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Abbreviations: AE, adverse event.aExpressed as n and percent of total subjects in each cohort.bAE led to discontinuation by subject owner, not by investigator.c0.007×1 mg/kg cohort: Demodex canis at day 44 post 0.5 mg/kg prednisolone on days 0 to 14; and 0.007×2 mg/kg cohort: Demodex injai at day 56 post 1.0 mg/kg prednisolone on days 0 to 14. Demodicosis cleared after one dose of milbemycin oxime, and each subject treated with LD-aminopterin for 24 (0.007×1 mg/kg cohort) and 9 (0.007×2 mg/kg cohort) months in the open-label segment without recurrence.Summary of clinical AEs by cohorta.
创建时间：
2015-12-02
