The closed C1-state mouse TRPM8 structure in complex with putative PI(4,5)P2

The closed C1-state mouse TRPM8 structure in complex with putative PI(4,5)P2 Descriptor: Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate Authors: Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. Deposit date: 2022-08-18 Release date: 2022-10-26 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.43 Å) Cite: Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022