five

Summary of Diagnoses.

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Figshare2015-12-02 更新2026-04-29 收录
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*Euthanised at end of study – mouse asymptomatic although CBC at euthanasia showed elevated WBCs (24.78 K/µL) and neutrophils (19.52 K/µL). Splenomegaly observed upon necropsy. H&E showed perivascular infiltration of the liver with invading cells approximately 50% MPO+ by IHC. FACS showed BM 54% Mac-1+/Gr-1+, 40% Ter119+ and spleen 25% Mac-1+/Gr-1+, 75% Ter119+.**NOS, not otherwise specified – mouse found dead, with hepatosplenomegaly. H&E showed extensive parenchymal invasion of blasts in the liver, spleen and kidney. IHC shows invasive cells to be B220-, CD3- and MPO-.
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2015-12-02
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