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Diastereoselective Synthesis of Functionalized Diketopiperazines through Post-transformational Reactions

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NIAID Data Ecosystem2026-03-10 收录
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A diversity-oriented access to diastereoselective arylidene 2,5-diketopiperazines is elaborated via a sequential Ugi post-transformation involving catalytic cyclization and oxidative Heck reaction sequence. This sequence offers an interesting multicomponent entry to a library of 2,5-diketopiperazines and arylidene 2,5-diketopiperazines under mild reaction conditions in good to excellent yields.

创建时间:
2017-11-06
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