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Crystal structure of BPTF bromodomain in complex with CB02-092

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of BPTF bromodomain in complex with CB02-092 Descriptor: 4-chloro-5-{4-[2-(dimethylamino)ethyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF Authors: Nithianantham, S, Fischer, M. Deposit date: 2021-03-16 Release date: 2022-02-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition J.Med.Chem., 64, 2021

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2021-03-16
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