Stress response associated genes differentially expressed in the <i>S. aureus</i> Δ<i>cymR</i> mutant strain compared to SH1000.

a. The SA numbers (N315 strain) for S. aureus genes correspond to those of AureoList (http://genolist.pasteur.fr/AureoList/). “*” indicates genes differentially expressed upon internalization of S. aureus in human epithelial cells [58]. b. The results obtained are representative of 8 hybridizations from 4 independent cultures in TSB medium with 2 mM cystine. The generated data sets were loaded into the GenoScript Database (http://genoscript.pasteur.fr)[25]. c. For qRT-PCR analysis, total RNA was extracted from S. aureus strains grown in TSB medium with or without 2 mM cystine. After reverse transcription, specific cDNAs was quantified by qRT-PCR using 16S rRNA gene for normalization. d. Differential expression of corresponding genes/proteins under indicated stress conditions including hydrogen peroxide (H2O2) [46], [47], diamide [47], paraquat [39], [47], nitrite [68] and nitrosative [69] stresses.