Cold/Cozy Mice - Finding the needles in the haystack of biomedical literature
收藏DataONE2017-06-15 更新2024-06-26 收录
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Problem Statement: the task facing biomedical scientists hoping to find publications that corroborate or debunk a hypothesis is akin to finding a needle in a haystack that keeps growing. Strategies that mine or summarize the scientific literature exist but have been largely focused on recovery of named entities (e.g. proteins, cells) or more sophisticated methods that make use of ontologies to recover also related terms and even, more recently, machine learning methods when there is sufficient training data. Approach: In our approach, we have extracted annotations of units and measures (U&M) in open-access scientific literature in ScienceDirect.com, which we then used in combination with contextual information (e.g. section of the paper) and regular expressions to identify the specific entity being measured (e.g. Housing Temperature). Results and Discussion: from a corpus of ~1.1M open access publications we found 299 relevant papers using the U&M approach combined with its surrounding contextual information. We found a clear prevalence of papers mentioning housing conditions in the range of 20-25°C, which is the approximate temperature range suggested by NIH guidelines. We also found a small increase in the number of papers describing mouse thermo-neutral housing conditions in the period after the observation that this variable has an impact in mice tumor growth (2014-2016). This dataset contains those results.
创建时间:
2023-11-22



