The miR-23-27-24 Clusters Drive Lipid-Associated Macrophage Proliferation in Obese Adipose Tissue
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE222351
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To determine how the miR-23-27-24 miRNA clusters regulate adipose tissue macrophage (ATM) programming in obesity, we placed control mice and mice containing a myeloid-specific deletion of the clusters on high-fat diet for 20weeks. Following dietary intervention, we performed bulk RNA-seq on F4/80 bead-selected ATMs from obese adipose tissue of control and knockout mice. Comparative gene expression profiling analysis of RNA-seq data for control and knockout ATMs from obese adipose tissue (4 biological replicates per genotype; 8 total)
创建时间:
2023-10-02



