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Cytosine methylation profiling in two dimensional and extracellular matrix based three-dimensional cultures of breast cancer cells

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NIAID Data Ecosystem2026-05-26 收录
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MDA-MB-231 cells were cultured in 2D and Matrigel based 3D culture for 4 days. Total DNA was extracted. Bisulfite treatment and BS-SEQ were carried out to profile global cytosine methylation in both culture conditions. Overall design: MDA-MB-231 cells were cultured in 2D and Matrigel based 3D culture for 4 days. Total DNA was extracted. Bisulfite treatment and BS-SEQ were carried out to profile global cytosine methylation in both culture conditions.

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2019-05-02
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