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Structure of the catalytic domain of PARP1 in complex with talazoparib

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Structure of the catalytic domain of PARP1 in complex with talazoparib Descriptor: (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one, Poly [ADP-ribose] polymerase 1 Authors: Gajiwala, K.S, Ryan, K. Deposit date: 2020-10-27 Release date: 2021-01-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. J.Biol.Chem., 296, 2021
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2020-10-27
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