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Molecular characterization of acral melanoma

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NIAID Data Ecosystem2026-05-26 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP151787
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资源简介:
Acral melanoma affects world populations irrespective of skin color. It has comparatively few single nucleotide mutations, but exhibits genomic instability characterized by structural rearrangements and amplifications. As acral melanoma harbors BRAF (GeneID:673) mutations at low frequencies, we searched for alternative therapeutic targets. We performed targeted deep sequencing of cancer-related genes on 122 acral melanomas and identified point mutations, structural rearrangements and copy number alterations.
创建时间:
2019-05-22
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