Immunoreactive pneumococcal proteins identified in this study by mass spectrometry.

a For spot numbers 1 through 8 refer to Fig. 1. Spot number 9 and 10 were identified from an independent experiment performed under similar experimental conditions.b Gene and protein annotations are according to the genome sequence of S. pneumoniae TIGR4 (GenBank accession no. AE005672). ORF, open reading frame.c Percentage of total protein sequence covered by the experimentally detected peptides.d Identification probability of the fragment match.e MASCOT scores greater than the cut-off value were considered statistically significant (p ≤ 0.05).Immunoreactive pneumococcal proteins identified in this study by mass spectrometry.