Copper- or Nickel-Enabled Oxidative Cross-Coupling of Unreactive C(sp3)–H Bonds with Azole C(sp2)–H Bonds: Rapid Access to β‑Azolyl Propanoic Acid Derivatives

β-Azolyl propanoic acid derivatives are frequently found in biologically active molecules and pharmaceuticals. Here, we report the oxidative heteroarylation of unactivated C­(sp3)–H bonds with azole C­(sp2)–H bonds via copper or nickel catalysis with the aid of removable bidentate auxiliary, which provides a rapid pathway to β-azolyl propanoic acid derivatives. A variety of azoles such as oxazole, benzoxazole, thiazole, benzothiazoles, benzimidazole, purine, and even [1,2,4]­triazolo­[1,5-a]­pyrimidine could be engaged in this protocol.