Oncogenic NRAS Signaling Differentially Regulates Survival and Proliferation in Melanoma.

ChEBI2012-08-08 更新2026-07-21 收录

黑色素瘤分子机制

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Oncogenic NRAS Signaling Differentially Regulates Survival and Proliferation in Melanoma.

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2012-08-08

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [ChIP-seq]

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Lung cancer remains the leading cause of cancer death. Genome sequencing of lung tumors from patients with Squamous Cell Carcinoma has identified SMAD4 to be frequently mutated. Here we used a novel m

NIAID Data Ecosystem90

Additional file 4: Table S3. of Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

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药物敏感性机制

Results of gene set enrichment analysis (GSEA) of the obtained three gene expression profiles of differences between sensitive and insensitive lung cancer cell lines. For that we used geneXplain platf

Figshare2018-02-14 更新60

Additional file 4: of Sunitinib-suppressed miR-452-5p facilitates renal cancer cell invasion and metastasis through modulating SMAD4/SMAD7 signals

癌症生物标志物

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Table S4. miR-452-5p expression in RCC and normal renal samples from TCGA RCCÂ dataset. (XLS 137Â kb)

NIAID Data Ecosystem60

Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-?B Pathway in Melanoma

黑色素瘤分子机制

NF-κB通路调控

Melanoma is a highly aggressive cancer with increasing incidence rates and a poor survival, particularly in patients with AJCC stage IV and advanced stage III. Deregulation of NF-kB is linked to diffe

NIAID Data Ecosystem70

Autoinhibited BRAF:(14-3-3)2:MEK complex with the BRAF RBD resolved

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靶向药物设计

Autoinhibited BRAF:(14-3-3)2:MEK complex with the BRAF RBD resolved Descriptor: 14-3-3 protein zeta/delta, Dual specificity mitogen-activated protein kinase kinase 1, N-(3-fluoro-4-{[4-methyl-2-oxo-7-

Protein Data Bank Japan2025-05-28 更新60

Oncogenic NRAS Signaling Differentially Regulates Survival and Proliferation in Melanoma.

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