Genetic variation influencing DNA methylation provides new insights into the molecular pathways regulating genomic function - Selected Supplementary Tables
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Selected Supplementary Tables - ST5, 7, 8 and 9
Supplementary Table 5. Cosmopolitan results. Cosmopolitan SNP-CpG associations identified through genome-wide association amongst Europeans and South Asians.
Supplementary Table 7. Cross-tissue replication. Results for further testing of the 11,165,559 cosmopolitan SNP-CpG associations identified (by genome-wide association in blood), in 4 isolated white cell subsets (CD4+ lymphocytes, CD8+ lymphocytes, monocytes and neutrophils), in adipocytes isolated from subcutaneous adipose tissue or visceral adipose tissue, and in whole adipose tissue.
Supplementary Table 8. Conditional analysis. Results of conditional analysis to identify SNPs independently associated with each of the ~360K CpG sites tested.
Supplementary Table 9. Sentinel SNPs and CpGs. Results of R2 pruning and locus merging to identify discrete genetic and methylation loci that are associated, and their respective sentinel SNPs and sentinel CpG sites.
Other files (e.g. annotation files and 'intermediate' processing files) referenced in our code are also provided.
创建时间：
2021-10-01
