Copper-Catalyzed Trifluoromethylation of Alkenes with Redox-Neutral Remote Amidation of Aldehydes
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Copper-Catalyzed_Trifluoromethylation_of_Alkenes_with_Redox-Neutral_Remote_Amidation_of_Aldehydes/3420841
下载链接
链接失效反馈官方服务：
资源简介：
A room-temperature
and one-pot synthesis of ε-CF3-substituted amides
via the copper-catalyzed trifluoromethylation
of alkenes with redox-neutral remote amidation of aldehydes is described.
This reaction is featured by an unprecedented 1,5-H atom abstraction
from aldehydic C–H bonds by α-CF3-alkyl radicals
resulting from the
radical trifluoromethylation of alkenes, thus enabling a new possibility
of the trifluoromethylation-initiated remote sp2 C–H
functionalization.
创建时间：
2016-06-13
