Vaccine inoculation route modulates early immunity and consequently antigen-specific immune response

ChEBI2021-05-17 更新2026-07-12 收录

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接种途径优化

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Vaccine inoculation route modulates early immunity and consequently antigen-specific immune response

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2021-05-17

Gamma-Irradiated Influenza Virus Uniquely Induces IFN-I Mediated Lymphocyte Activation Independent of the TLR7/MyD88 Pathway

TLR/MyD88信号通路

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BackgroundWe have shown previously in mice, that infection with live viruses, including influenza/A and Semliki Forest virus (SFV), induces systemic partial activation of lymphocytes, characterized by

NIAID Data Ecosystem40

Table_3_Inactivated tick-borne encephalitis vaccine elicits several overlapping waves of T cell response.xlsx

T细胞免疫应答

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The development and implementation of vaccines have been growing exponentially, remaining one of the major successes of healthcare over the last century. Nowadays, active regular immunizations prevent

NIAID Data Ecosystem30

Molecular signatures in a Hepatitis B Vaccine-immunized neonatal Tissue Construct in vitro correlate with antibody response in vivo

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多组学分析

We employ our 3-dimensional tissue construct model that was previously used to investigate and replicate human age- specific vaccine responses in vivo, to a) gain insights into vaccine-induced OMIC si

NIAID Data Ecosystem20

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

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适应性免疫优化

Whooping cough caused by Bordetella pertussis is a re-emerging infectious disease despite the introduction of safer acellular pertussis vaccines (Pa). One explanation for this is that Pa are less prot

Figshare2016-01-18 更新30

Role of PKR and Type I IFNs in Viral Control during Primary and Secondary Infection

病毒免疫调节

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Type I interferons (IFNs) are known to mediate viral control, and also promote survival and expansion of virus-specific CD8+ T cells. However, it is unclear whether signaling cascades involved in elic

NIAID Data Ecosystem20

Vaccine inoculation route modulates early immunity and consequently antigen-specific immune response

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