WES analysis of edited human hematopoietic stem/progenitor cells
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA850889
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资源简介：
We have developed a therapeutic strategy for beta-hemoglobinopathies aimed at reactivating fetal hemoglobin expression in red blood cells derived from human hematopoietic stem/progenitor cells edited with CRISPR/Cas9 nucleases, cytidine or adenine base editors targeting the fetal gamma-globin promoters. Here, we report the WES changes occurring in human hematopoietic stem/progenitor cells (obtained from healthy donors) 6 days after transfection with CRISPR/Cas9 nucleases, cytidine or adenine base editors.
创建时间：
2022-06-20
