Vitamin D status and unadjusted and adjusted levels of depressive symptoms.

Group comparisons were calculated with multivariate analysis of variance (unadjusted) or covariance with full adjustment for age, sex, season, skin pigmentation, obesity, elevated liver enzyme levels, elevated C-reactive protein levels, psychiatric comorbidity (anxiety disorder, posttraumatic stress disorder, somatoform disorder, eating disorder), recurrent depressive episode, medication (vitamin D supplements, number of antidepressants, use of neuroleptics, use of anticonvulsants, number of pain medications), and vitamin D assay.1 significantly higher with vitamin D deficiency than vitamin D insufficiency.2 significantly higher with vitamin D deficiency than vitamin D sufficiency.3 significantly higher with vitamin D insufficiency than with vitamin D sufficiency.BDI-II, Beck Depression Inventory-II; BSI-D, depression subscale of the Brief Symptom Inventory; HADS-D, depression subscale of the Hospital Anxiety and Depression Scale.Vitamin D status and unadjusted and adjusted levels of depressive symptoms.