Additional file 1 of Mendelian randomization and colocalization reveal potential causal effects of average daily gain on carcass composition and reproductive traits in pigs

Additional file 1: Table S1. Description of the meta-GWAS summary statistics used in the GSMR-based Mendelian randomization and colocalization analyses. Table S2. Summary of candidate genes associated with carcass composition and reproductive traits, directly annotated to GSMR instrumental SNPs. Table S3. Summary of colocalization analysis results and numbers of SNPs used across carcass composition and reproductive traits. Table S4. Genomic coordinates and annotations of genes in the top colocalized region. Table S5. Significant cis-eQTLs associated with MC4R expression in pig frontal cortex. Table S6. Significant cis-eQTLs associated with CDH20 expression in pig muscle tissue. Table S7. LD between the top colocalized SNPand cis-eQTL SNPs in the MC4R and CDH20 genes. Table S8. Functional annotation of top colocalized and high-LD SNPs at the MC4R and CDH20 loci, including genomic positions, predicted variant consequences, and associated traits from QTLdb.