PCMDB: A database of methylated genes in pancreatic cancer

PCMdb: Pancreatic Cancer Methylation Database Welcome to the official repository for PCMdb, a comprehensive and manually curated database dedicated to DNA methylation in pancreatic cancer. This resource was developed to support researchers working in cancer biology, epigenetics, biomarker discovery, bioinformatics, and translational oncology. Web Server: http://crdd.osdd.net/raghava/pcmdb/ Citation Nagpal, G., Sharma, M., Kumar, S., Chaudhary, K., Gupta, S., Gautam, A., & Raghava, G. P. S. (2014).PCMdb: Pancreatic Cancer Methylation Database.Scientific Reports, 4, 4197.https://doi.org/10.1038/srep04197. https://github.com/Piyushh1104/PCMDB.git About the Database PCMdb is a specialized repository that provides experimentally validated methylation information for genes associated with pancreatic cancer. The database consolidates methylation studies from published literature into a single platform to facilitate biomarker discovery and cancer research. The database integrates information related to: DNA methylation status Pancreatic cancer subtypes Tissue and cell line data Experimental techniques Drug resistance associations Biomarker information Data was manually curated from published research articles and integrated with external biological resources. Key Features Large Curated Dataset 65,907 total entries 4,342 unique genes Data compiled from 109 research articles Includes: 53,565 cell line entries 12,342 tissue sample entries Covers 88 pancreatic cancer cell lines Covers 3,078 tissue samples Methylation Categories The database classifies methylation data into five categories: High methylation Intermediate methylation Low methylation Altered methylation Not known Approximately: 47.22% entries show high methylation 10.87% entries show low methylation