Crystal structure of human FTO in complex with small-molecule inhibitors
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of human FTO in complex with small-molecule inhibitors Descriptor: (E)-3-[3-nitro-4,5-bis(oxidanyl)phenyl]-2-(1,3-oxazinan-3-ylcarbonyl)prop-2-enenitrile, Alpha-ketoglutarate-dependent dioxygenase FTO,Alpha-ketoglutarate-dependent dioxygenase FTO, ZINC ION Authors: Wang, Y, Cao, R, Peng, S, Zhang, W, Huang, N. Deposit date: 2018-08-05 Release date: 2019-06-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1. Sci Transl Med, 11, 2019
创建时间：
2018-08-05
