five

ChIP-sequencing of PRMT1 proficient and deficient microglia

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE205309
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ChIP_sequencing analysis defined a novel role for the PRMT1 in microglia during normal and 0.2% cuprizone diet 5weeks We then performed ChIP analysis using data obtained from ChIP-seq of microglia at two time points Microglia ChIP profiles of 4-6 weeks-old wild-type (PRMT1Ifl/fl) and microglia specific knockout (PRMT1fl/fl; cx3r1cre-ert2) mice during normal and 0.2% cuprizone diet 5 weeks Samples 1 to 10 (GSM6210097-GSM6210106) represent anti_H3K27Ac ChIP; while Samples 11 to 19 (GSM6210107-GSM6210115) are the inputs; they consisted in 1% aliquots of the samples taken post-sonication, but before IP.
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2022-07-14
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