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Potassium homeostasis imbalance reprograms PGE2 metabolism in glioma-associated macrophages to promote immunosuppression microenvironment

NIAID Data Ecosystem2026-05-10 收录

胶质瘤免疫微环境

细胞代谢重编程

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP513074 数据链接链接失效反馈

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资源简介：

To investigate the impact of high K+ in innate immune microenvironment of glioma.

应用场景：

创建时间：

2025-12-31

胶质瘤免疫微环境

肿瘤预后标志物

Patients diagnosed with glioblastomas continue to have a dismal prognosis, highlighting the need for a better characterization of these tumors in order to identify more efficient therapies. In this st

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Table_1_Immune Infiltration-Related Signature Predicts Risk Stratification and Immunotherapy Efficacy in Grade II and III Gliomas.XLSX

胶质瘤免疫微环境

免疫治疗疗效

Background: Tumor microenvironment, especially infiltrating immune cell, is crucial for solid tumors including glioma. However, the hub genes as well as their effects on patient prognosis and immunoth

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Supporting data for "Phosphorylated SOX9 Drives Neuroinflammatory Astrocyte Subtypes by Boosting Hexokinase 1 in Neuropathic Pain"

神经病理机制

细胞代谢重编程

Neuropathic pain (NP) is elicited by multiple etiologies, including injuries or diseases, casing spontaneous and persistent pain, which exerts adverse impacts on patients’ quality of life. Currently,

DataCite Commons2024-08-19 更新20

Table3_Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes.xlsx

病毒性心肌损伤机制

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Coronavirus disease 2019 (COVID-19) is associated with adverse impacts in the cardiovascular system, but the mechanisms driving this response remain unclear. In this study, we conducted “pseudoviral i

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Table1.PDF

胶质瘤免疫微环境

IDH1基因

Background: Malignant gliomas are heterogeneous brain tumors with the potential for aggressive disease progression, as influenced by suppressive immunoediting. Given the success and enhanced potential

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Potassium homeostasis imbalance reprograms PGE2 metabolism in glioma-associated macrophages to promote immunosuppression microenvironment

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