Exclusive enteral nutrition induced sustained changes in the microbiota and improved inflammatory bowel disease in a pediatric patient with chronic granulomatous disease

Exclusive enteral nutrition induced sustained changes in the microbiota and improved inflammatory bowel disease in a pediatric patient with chronic granulomatous disease. We successfully treated a patient with inflammatory bowel disease and chronic granulomatous disease using exclusive enteral nutrition (EEN). We analyzed the stool microbiome of the presented patient before, during and after EEN for 5 years. Wee compared post-EEN samples to samples from 15 healthy participants and 12 patients with CGD. EEN induced sustained changes in the intestinal microbiota including enrichment of bacterial taxa associated with intestinal health. Corresponding author Emilia Liana Falcone, M.D., Ph.D. Montreal Clinical Research Institute (IRCM) 110 Pine Avenue West Montreal, Quebec H2W 1R7 Canada Office: [phone] Mobile: [phone] [e-mail] Contact: Emilia Liana Falcone. This submission was powered by METAGENOTE (https://metagenote.niaid.nih.gov).