Comparison of binding predictions of selected peptides of PPE68 to HLA-DR alleles using various computational methods and IFN-γ responses of PBMCs from 30 healthy subjects.

aThe results are shown as number of HLA-DR molecules predicted to bind/number of HLA-DR molecules tested for binding to a given peptide and the percentages are given in brackets.bThe results are given as the number of subjects positive/the number of subjects tested with each peptide and the percentages of positi9ve responders are given in brackets.The %binding values suggesting promiscuous HLA-DR binding (binding to >50% HLA-DR alleles) and the strong responses (Median IFN-γ concentration >5 U/ml and %positive ≥70%) are given in bold face.