Potent beta-secretase 1 inhibitor
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3ixk
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Potent beta-secretase 1 inhibitor Descriptor: Beta-secretase 1, N-[(2S,3S,5R)-1-[(3,5-difluorophenyl)methoxy]-3-hydroxy-5-methyl-6-[[(2S)-3-methyl-1-oxo-1-(phenylmethylamino)butan-2-yl]amino]-6-oxo-hexan-2-yl]-5-(methyl-methylsulfonyl-amino)-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide Authors: Borkakoti, N, Lindberg, J.D, Nystrom, S. Deposit date: 2009-09-04 Release date: 2010-09-08 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core. Eur.J.Med.Chem., 45, 2010
创建时间：
2009-09-04
