Lung alveolar macrophages are self-renewing tissue resident macrophages primarily relying upon GM-CSF signal as a main source. We used microarrays to detail the global programme of gene expression und
Mimicry of neuronal features is emerging as malignant regulator of cancer growth and metastasis. Neuroendocrine (NE) cancers including small cell lung cancers (SCLC) have been shown to share expressio
Alveolar macrophages (AMs) are pivotal in maintaining lung homeostasis and orchestrating responses to infections. While traditionally perceived as fixed tissue-resident macrophages (TRM) with limited
RationaleThe accumulation of macrophages in the airways and the pulmonary interstitium is a hallmark of cigarette smoke-associated inflammation. Notably, pulmonary macrophages are not a homogenous pop