Crystal structure of PAK1 kinase domain in complex with FRAX597 inhibitor
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Crystal structure of PAK1 kinase domain in complex with FRAX597 inhibitor Descriptor: 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, Serine/threonine-protein kinase PAK 1 Authors: Maksimoska, J, Marmorstein, R. Deposit date: 2012-04-18 Release date: 2013-08-28 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.01 Å) Cite: FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas. J.Biol.Chem., 288, 2013
创建时间：
2012-04-18
