Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
收藏Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state) Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ... Authors: Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2023-05-08 Release date: 2023-09-06 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
创建时间：
2023-05-08
