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A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome. A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome

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NIAID Data Ecosystem2026-05-01 收录
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Oligodendrocyte progenitor cells (OPCs) derived from two WS patient lines (c2002_mutant and 2010_Mutant) and their respective isogenic line (Cl7_Ctrl and 2g6_Ctrl) were sequenced to determine transcriptomic differences Overall design: 6 replicates of each Patient and Isogenic iPSC derived OPCs were sequenced

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2024-04-17
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