Tumor infiltrating CD8+ Tex cells dictate divergent survival outcomes in pre- vs post-menopausal ER+ breast cancer
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190169
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资源简介：
We identify subsets of BC tumors infiltrated by CD8+ T cells with characteristic features of exhausted T cells (TEX). Tumors with abundant CD8+ TEX exhibit a distinct tumor microenvironment marked by amplified interferon-γ signaling related pathways and higher PD-L1 expression. ER+ tumors were segregated into TEX ‘high’ (TEXhi) and TEX ‘low’ (TEXlo) tumors as defined by above and below 5% TEX of CD8+ TILs based on FACS.
创建时间：
2024-03-11
