Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol
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https://figshare.com/articles/dataset/Total_Synthesis_of_the_Resorcyclic_Acid_Lactone_Spiroketal_Citreoviranol/3792495
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资源简介:
The first total synthesis of resorcyclic acid lactone spiroketal citreoviranol (1) is described. The synthesis was completed in nine steps and via Sonogashira cross-coupling, gold-catalyzed cyclization, and an unusual base-induced ketalization. The relative and absolute stereochemistry of citreoviranol was unambiguously confirmed using 2D NMR spectroscopy and X-ray crystallography.
创建时间:
2016-09-12



