High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping

We describe the preparation of rapid
prototyped parallelized microfluidic drop-maker devices. The manufacturing
technique facilitates stacking of the drop-makers vertically on top
of each other allowing for a reduced footprint and minimized dead-volume
through efficient design of the distribution channels. We showcase
the potential of the additive manufacturing technique for microfluidics
and the performance of the parallelized device by producing large
amounts of microgels with a diameter of ca. 500 μm, a size that
is inaccessible using traditional synthetic approaches.