Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Double Mutant (L50F and E166V) in Complex with Inhibitor Nirmatrelvir
收藏Protein Data Bank Japan2026-03-11 更新2026-03-21 收录
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) Double Mutant (L50F and E166V) in Complex with Inhibitor Nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 Authors: Lin, M, Liu, X. Deposit date: 2022-10-13 Release date: 2023-10-11 Last modified: 2026-03-11 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature, 622, 2023
创建时间：
2022-10-13
