Crystal structure of Zika NS2B-NS3 protease in complex with follow-up compound EOS41783 from ECBL

Crystal structure of Zika NS2B-NS3 protease in complex with follow-up compound EOS41783 from ECBL Descriptor: Genome polyprotein, Serine protease subunit NS2B, ~{N}-[(2~{S})-2-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-yl)propyl]-5-methyl-furan-2-carboxamide Authors: Benz, L.S, Wollenhaupt, J, Jirgensons, A, Miletic, T, Mueller, U, Weiss, M.S. Deposit date: 2025-06-06 Release date: 2025-10-29 Last modified: 2025-12-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: From fragments to follow-ups: rapid hit expansion by making use of EU-OPENSCREEN resources. Rsc Med Chem, 16, 2025