Lipid signalling enforces functional specialization of Treg cells in tumours [scRNA-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP302716
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资源简介：
Metabolic reprogramming enforces Treg cell functional specialization in tumors by coordinating fatty acid biosynthesis and inhibitory receptor signaling pathways. These findings point to new avenues to selectively targeting intratumoral Treg cells for cancer therapy. Overall design: We used scRNA-seq to compare CD45+ immune cells composition in B16 tumor microenvironment of wild-type mice and mice with Scap Treg-specific deletion.
创建时间：
2021-03-02
